Insight

What Makes a Successful Science and Tech Cluster?

23.10.25

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The dynamism of the Oxford-Cambridge Corridor is highlighted in a new analysis from the World Intellectual Property Organisation (WIPO). The analysis looks at the number of academic articles, patents and venture capital raised in 237 cities. 

If innovation is measured simply in terms of volume, then inevitably the most innovative places are mega cities such as Shenzhen-Hong Kong, or Tokyo. However, if the figures are adjusted for population size to identify concentrations of innovation, then Cambridge ranks as the second most innovative location in the world behind Silicon Valley and Oxford ranks fifth.

Innovation Intensity and Academic Excellence
Source: WIPO Global Innovation Index 2025, Times Higher Education World University Ranking 2026.
So what makes a successful science and tech cluster?

 

The obvious answer is a world class university which acts as a nursery for spin-outs and is a magnet for established companies who wish to collaborate with leading academics. Oxford ranks first in The Times Higher Education World University Rankings and Cambridge third. Furthermore, Silicon Valley is home to both Stanford (5th) and Berkeley (9th) and Boston has MIT (2nd) and Harvard (5th). There is a significant correlation (0.7) between the two rankings.

However, a world class university is not a guarantee that a city will also have a thriving science and tech cluster. Both Princeton and Yale in the USA are top universities, but neither feature in the WIPO rankings. That suggests that other ingredients are also required.

One important additional factor is the presence of a culture of starting businesses and risk taking.

Historically, that was frowned upon by UK universities, but attitudes have changed over the last 20 years as UK universities have looked to diversify their income and emulate their US counterparts which earn significant royalties from intellectual property. Part of the reason why Stockholm scores highly in the WIPO rankings is the so-called professor’s privilege. Unlike in other countries, Swedish academics own the intellectual property they create, rather than it being assigned to their university.

It follows that another important element for a successful science and tech cluster is venture capital.

Initially most university spin-outs have no revenue, so they cannot borrow from banks to fund their product development. Instead, they have to rely upon angel investors and venture capital funds. Both Oxford and Cambridge universities have set up their own venture capital funds which take stakes in spin-outs and their global reputation means that they have been able attract investment from international as well as domestic investors.

This has also created a virtuous circle whereby local entrepreneurs who have been successful have then become mentors to later spin-outs and re-invested their profits. The ecosystem has attracted further venture funds expanding the enterprise potential of the location.

By contrast, it is much more difficult for spin-outs elsewhere in the UK to raise money.

Image of 3187 Science and Tech Clusters Blog Graphics CHART v3
Source: Bidwells, PitchBook, 2025


Universities outside the Golden Triangle of London, Oxford and Cambridge have accounted for over half of all life science spin-outs in the last decade, but attracted only 39% of the total venture capital raised.

However, even if a city has a strong university and access to venture capital, that is not the whole story.

Ningde, Helsinki and Eindhoven are all tech hubs, but none of them are in the top 12 of the Times university ranking, or even the top 100. Instead, their success is due to the presence of companies with leading technology. Ningde is home to CATL which is a world leader in batteries for electric vehicles, Eindhoven is the base for Philips Electronics and Helsinki is home to Nokia.

The risk for these “company towns” is that their fortunes are tied to one business which, sooner or later, loses its technological edge. Both Nokia and Philips have been through difficult times and downsized, but new companies have emerged which have built on their technology. ASML which is a key supplier to manufacturers of semi-conductors is based in Eindhoven and Helsinki has become a centre for mobile gaming.

The final challenge for a city with a successful science and tech cluster is how to accommodate its growth without destroying what makes the city an attractive place to live.

Virtually all the cities at the top of the WIPO ranking suffer from a shortage of housing, not just Oxford and Cambridge.

Different cities have attempted to solve the problem in different ways. For example, Copenhagen has expanded outwards and used land value capture to fund new metro lines and other public infrastructure. Alternatively, Ann Arbor is currently debating proposals to re-zone neighbourhoods which will allow for higher densify housing, while preserving open spaces.

In conclusion, what makes a successful science and tech cluster is: an anchor institution with a technological lead, be it a university, or a company; a culture which encourages entrepreneurship and risk taking; access to venture capital and local government with a long-term vision to foster growth.

As we look to enhancing economic growth and productivity in the UK it is positive we have two of the world’s most inventive cities at its core.

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Mark Callender

Research Partner

Mark was appointed as research partner to focus on high-growth sectors, including renewable energy, science and technology, and natural capital markets.

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